feuC

168

[wiki|ABC transporter ]for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)

locus: BSU_01610

Molecular weight: 42.91 kDa

pI: 10.44

Protein length: 336 aa

Gene length: 1011 bp

function: [wiki|acquisition of iron]

product: [wiki|ABC transporter ]for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)

essential: no

synonyms: feuC

List of homologs in different organisms, belongs to COG0609 (Galperin et al., 2021)

Gene

Coordinates: 180,344 → 181,354

Phenotypes of a mutant

• severe growth inhibition upon addition of subinhibitory concentrations of mirubactin C [pubmed|36312962]

Advertisement

The protein

Protein family

• [wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
• [wiki|FecCD subfamily] (according to UniProt)

Structure

• [PDB|4G1U] (heme transporter from Yersinia pestis, 31% identity) [pubmed|23142986]
• [AF|P40411]

Paralogous protein(s)

• [protein|EC98685EE0E3CE6CE8DC33409481AE96315279AC|fhuG]

[wiki|Localization]

• cell membrane [Pubmed|10092453]

Expression and Regulation

Other regulations

• [protein|E15E9F88B0E03FE8834C646369D2F4B4E713EF41|citB]: translation control

Biological materials

Mutant

• BKE01610 (Δ[gene|F38F6D4841B3044EA0496B3A1C1D484018BDFEA4|feuC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE01610 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCGATGAACAATGCAT,  downstream forward: _UP4_AAGCAAAAAAAGGGGGAGAA
• BKK01610 (Δ[gene|F38F6D4841B3044EA0496B3A1C1D484018BDFEA4|feuC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK01610 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCGATGAACAATGCAT,  downstream forward: _UP4_AAGCAAAAAAAGGGGGAGAA

References

• 19746494,16672620,10092453,16889643,17725565,12354229,10468622,29133393,23142986,36312962