holA

holA
168

DNA polymerase III, delta subunit, part of the clamp-loader complex and the [wiki|replisome]

locus
BSU_25560
Molecular weight
40.35 kDa
pI
6.23
Protein length
Gene length
function
[category|SW.3.1.1|DNA replication]
product
DNA polymerase III, delta subunit
essential
yes
ec
2.7.7.7
synonyms
holA, yqeN

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1466 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,636,096 → 2,637,139
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
required for bacteriophage SPP1 replication [Pubmed|23268446]
[wiki|Domains]
domain I: aa 1 - 143, RecA-like fold [Pubmed|23525462]
domain II: aa 144 - 214, four alpha helices [Pubmed|23525462]
domain III: aa 215 - 339, seven alpha helices [Pubmed|23525462]
Structure
[PDB|3ZH9] [Pubmed|23525462]
[AF|P54459]
[wiki|Localization]
Nucleoid (Mid-cell) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|CE70B471811371D454A74F67279974BF264205C2|holA]
description
[Pubmed|22383849]
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[gene|CE70B471811371D454A74F67279974BF264205C2|holA]

2024-03-17 21:09:42

Jstuelk

55

d4f1afade58cef408cd2b5f67f8d5ec44963b288

5386793F90265B36A6A6C1C4BD1A02A884F43AE2

References
16479537,20122408,23525462,23268446,23563155

CE70B471811371D454A74F67279974BF264205C2

Page visits: 4253

Time of last update: 2024-03-29 08:01:26

Author of last update: Jstuelk