nupN
168
lipoprotein, part of guanosine transporter
locus
BSU_31540
Molecular weight
37.19 kDa
pI
4.82
function
uptake of guanosine
product
lipoprotein, part of guanosine transporter
essential
no
synonyms
nupN, yufN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1744 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,239,930 3,241,009
Phenotypes of a mutant
a ''[gene|19BA45BD691BBA4B23C4741C63DB729AA5D30FDA|nupN] [gene|C333F405F597FF260FFA0EC616B8CF6BF454815B|nupG]'' double mutant is unable to utilize externally provided guanosine [Pubmed|21926227]
The protein
Protein family
BMP lipoprotein family (with [protein|4DAB7847EA3848A34432C80124464543FA3DCA0F|med], according to UniProt)
Structure
[PDB|2FQW] (from Treponema pallidum, 45% identity) [pubmed|16418175]
[AF|O05252]
[wiki|Localization]
cell membrane (according to UniProt), membrane associated [Pubmed|18763711]
Biological materials
Mutant
MGNA-B553 (yufN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1552 NBRP B. subtilis, Japan]
BKE31540 ([gene|19BA45BD691BBA4B23C4741C63DB729AA5D30FDA|nupN]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGATATAACCCCCCAGAA, downstream forward: _UP4_TAAGAATCGCAGGGATAAGG
BKK31540 ([gene|19BA45BD691BBA4B23C4741C63DB729AA5D30FDA|nupN]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGATATAACCCCCCAGAA, downstream forward: _UP4_TAAGAATCGCAGGGATAAGG
References
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Time of last update: 2024-04-24 05:32:30
Author of last update: Melvin.boenninger