ykuQ

ykuQ
168

tetrahydrodipicolinate acetylase

locus
BSU_14180
Molecular weight
24.84 kDa
pI
4.68
Protein length
Gene length
function
biosynthesis of lysine and peptidoglycan
product
tetrahydrodipicolinate acetylase
essential
yes
ec
2.3.1.89
synonyms
ykuQ, dapH

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2171 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,488,973  1,489,683
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O --> CoA + L-2-acetamido-6-oxoheptanedioate (according to UniProt)
Protein family
[wiki|Transferase hexapeptide repeat family] (according to UniProt)
Structure
[PDB|3R8Y] (from ''Bacillus anthracis'', 80% identity, 96% similarity)
[AF|O34981]
Expression and Regulation
Operons
genes
[gene|716FE06124544C05CC34BA2E643B4DBD27F04998|ykuQ]-[gene|D6F1906CE8386F78F451D6B794F74DE4AD25AC9C|ykuR]-[gene|3E7E0342AA86AFCC95F5CD5BEA5B10166DCE2721|ykuS]
description
[Pubmed|22383849]
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[gene|716FE06124544C05CC34BA2E643B4DBD27F04998|ykuQ]→[gene|3E7E0342AA86AFCC95F5CD5BEA5B10166DCE2721|ykuS]

2024-01-23 21:27:00

Jstuelk

53

cd9e2fdc932f01581710e276a91df586a6d39c25

30EDD1FD8E81987B92126BC0CB4F32A7343A78F7

Biological materials
Mutant
MGNA-B340 (ykuQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1339 NBRP B. subtilis, Japan]

716FE06124544C05CC34BA2E643B4DBD27F04998

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Time of last update: 2024-03-28 12:56:56

Author of last update: Jstuelk