ylxM

ylxM
168

putative signal recognition particle (SRP) component

locus
BSU_15970
Molecular weight
13.02 kDa
pI
4.54
Protein length
Gene length
function
presecretory protein translocation
product
putative signal recognition particle (SRP) component
essential
no
synonyms
ylxM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2739 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,671,828  1,672,160
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The protein
Protein family
UPF0122 family (single member, according to UniProt)
Structure
[PDB|1XSV] (from ''Staphylococcus aureus'', 54% identity)
[AF|P37104]
Expression and Regulation
Operons
genes
[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]
description
[pubmed|36840557]
regulation
the mRNA is processed between [gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh] and [gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|ricA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|ricF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|ricT] complex [Pubmed|29794222]
expression
expression is decreased upon depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8335643], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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Array

2024-03-21 22:21:17

Jstuelk

26

0C22E9A74563E6DB840352CF68BC5D70BBD11EAB

0C22E9A74563E6DB840352CF68BC5D70BBD11EAB

genes
[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|khpA]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
description
[Pubmed|29794222]
regulation
the mRNA is processed between [gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh] and [gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|ricA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|ricF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|ricT] complex [Pubmed|29794222]
expression
expression is decreased upon depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8335643], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]→[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]

2024-02-07 15:26:05

Jstuelk

82

4F2FF9A3B937EE85312D0B0F9DA494E4B44E2297

417C7007C2492335257F8AEF606BB8627753757F

Biological materials
Mutant
BKE15970 ([gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15970 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGAGCTCTCCCCTTTG,  downstream forward: _UP4_AAATTAGATTAGGAGGCGGC
BKK15970 ([gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15970 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGAGCTCTCCCCTTTG,  downstream forward: _UP4_AAATTAGATTAGGAGGCGGC
References
8335643,24659773,36840557,36815589

8F559BFC80FE56EA0389A2336F4E9E6908562BCB

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Time of last update: 2024-03-28 19:27:30

Author of last update: Jstuelk