yrpC

yrpC
168

glutamate racemase

locus
BSU_26810
Molecular weight
29.73 kDa
pI
6.74
Protein length
Gene length
function
peptidoglycan precursor biosynthesis
product
glutamate racemase
essential
no
ec
5.1.1.3
synonyms
yrpC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0796 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,738,308 → 2,739,105
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The protein
Catalyzed reaction/ biological activity
L-glutamate --> D-glutamate (according to UniProt)
Protein family
aspartate/glutamate racemases family (with [protein|36FF9F097682D8BA8D7359BFEAF71ACE8E9E90D8|racE] and [protein|2ABCC493C6CA847A7BC65B1200A9B6490621462A|racX], according to UniProt)
Structure
[PDB|2JFN] (from ''Escherichia coli'', 36% identity, 54% similarity) [Pubmed|17568739]
[AF|O05412]
Paralogous protein(s)
[protein|36FF9F097682D8BA8D7359BFEAF71ACE8E9E90D8|racE]
Expression and Regulation
Operons
genes
[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]
description
[Pubmed|22383849]
regulation
expressed only in minimal medium, not in complex medium [Pubmed|15347750]
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[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]

2024-03-26 16:36:50

ghost

43

b4ec43d91b5f58377af4a536c4c00f3652e1dd55

F17EDDC1025D199F657E1E5D7F95943948F81971

Biological materials
Mutant
MGNA-A867 (yrpC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/867 NBRP B. subtilis, Japan]
BKE26810 (Δ[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCACTTCTCACGCTTTCT,  downstream forward: _UP4_TGAATGTAAATGAAAAAGAC
BKK26810 (Δ[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCACTTCTCACGCTTTCT,  downstream forward: _UP4_TGAATGTAAATGAAAAAGAC
References
15347750,22383849,25777674

BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB

Page visits: 1663

Time of last update: 2024-03-26 04:51:07

Author of last update: Melvin.boenninger