ythP

168

similar to [wiki|ABC transporter] (ATP-binding protein)

locus: BSU_30010

Molecular weight: 26.36 kDa

pI: 5.26

Protein length: 236 aa

Gene length: 711 bp

function: unknown

product: [wiki|ABC transporter] (ATP-binding protein)

essential: no

synonyms: ythP

List of homologs in different organisms, belongs to COG1131 (Galperin et al., 2021)

Gene

Coordinates: 3,071,400  3,072,110

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The protein

Protein family

• [wiki|ABC transporter superfamily] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transporter domain] (aa 4-255) (according to UniProt)

Structure

• [PDB|4RVC] (from Geobacillus kaustophilus, 44% identity) [pubmed|25724946]
• [AF|O34977]

Paralogous protein(s)

• [protein|59A7B26F810D7FEB07C176A8B2ECF6B83803DE49|ecsA]

Expression and Regulation

Operons

• genes: [gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]-[gene|3ACDFBD5615510FA015486C7A3C7023226EC3476|ythQ]

  description: [Pubmed|11866510]

  regulation

  • expressed under conditions of cell wall stress ([protein|search|SigW]) [Pubmed|11866510,12207695]

  sigma factors

  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|11866510,12207695], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]

Biological materials

Mutant

• MGNA-A817 (ythP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/817 NBRP B. subtilis, Japan]
• BKE30010 ([gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30010 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAACTCACTCACCTCCAA,  downstream forward: _UP4_AAGGCAGTTCAAGGTGATCG
• BKK30010 ([gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30010 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAACTCACTCACCTCCAA,  downstream forward: _UP4_AAGGCAGTTCAAGGTGATCG

References

• 10092453,11866510,12207695,25724946