ytkL

168

general stress protein

locus: BSU_29410

Molecular weight: 24.68 kDa

pI: 5.01

Protein length: 227 aa

Gene length: 684 bp

function: unknown

product: unknown

essential: no

synonyms: ytkL

List of homologs in different organisms, belongs to COG2220 (Galperin et al., 2021)

Gene

Coordinates: 3,009,915  3,010,598

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The protein

Protein family

• UPF0173 family (with [protein|888BC7D4C610DEBA6D46638F5FA1E86C1D433F48|yddR], according to UniProt)

Structure

• [PDB|3X2Z] (from Thermotoga maritima, 49% identity)
• [AF|Q795U4]

Expression and Regulation

Operons

• genes: [gene|3BF3EC6B3139744D968B2FF18CBEEEF15B591AFF|ytkK]-[gene|8B28AA1A88FA56C9F4742F668B28F3323715D948|ytkL]

  description: [Pubmed|22383849]

  regulation

  • induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|15805528]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]

Biological materials

Mutant

• MGNA-A157 (ytkL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/157 NBRP B. subtilis, Japan]
• BKE29410 ([gene|8B28AA1A88FA56C9F4742F668B28F3323715D948|ytkL]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTTCACCTCGTCAC,  downstream forward: _UP4_TAAACCGTGAAACCATCTCC
• BKK29410 ([gene|8B28AA1A88FA56C9F4742F668B28F3323715D948|ytkL]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTTCACCTCGTCAC,  downstream forward: _UP4_TAAACCGTGAAACCATCTCC

References

• 15805528,9387221