ytpQ

ytpQ
168

unknown

locus
BSU_29830
Molecular weight
30.89 kDa
pI
5.3
Protein length
Gene length
function
maybe involved in iron homeostasis
product
unknown
essential
no
ec
null
synonyms
ytpQ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4848 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,053,364  3,054,173
Phenotypes of a mutant
derepression of the [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur] and [protein|00BCAAE16576DC5426A652580C69A570FC7A1C2C|perR] regulons [Pubmed|21949854]
elevated oxidative protein damage upon exposure of the cells to methylglyoxal [Pubmed|21949854]
the ''[gene|2C6386E9A63F410558D168798D077DF91590F454|spx] [gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]'' doulbe mutant shows reduced growth in minimal medium and hypersensitivity to methylglyoxal [Pubmed|21949854]
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The protein
Protein family
UPF0354 family (single member, according to UniProt)
Structure
[AF|O34496]
Expression and Regulation
Operons
genes
[gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]-[gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]-[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]
description
[Pubmed|21949854]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|21949854], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21949854], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]→[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]

2024-03-21 18:56:59

ghost

68

e3075f4343f005e46bbf1f8f6de68bdd8b77fdec

DE889C52EC07AB93CD9959D9559B3C7B78EAC111

Biological materials
Mutant
MGNA-A437 (ytpQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/437 NBRP B. subtilis, Japan]
BKE29830 ([gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCAAACCGATGTCCT,  downstream forward: _UP4_AAGGATTAGAAAGGATTTTT
BKK29830 ([gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCAAACCGATGTCCT,  downstream forward: _UP4_AAGGATTAGAAAGGATTTTT
References
21949854

886EF2F8A9E031FDF919E01A858C1DBC1AFF1188

Page visits: 1588

Time of last update: 2024-03-28 17:30:46

Author of last update: Melvin.boenninger