ywhC

168

similar to site-2 protease

locus: BSU_37530

Molecular weight: 24.56 kDa

pI: 9.74

Protein length: 219 aa

Gene length: 660 bp

function: unknown

product: unknown

essential: no

synonyms: ywhC

List of homologs in different organisms, belongs to COG1994 (Galperin et al., 2021)

Gene

Coordinates: 3,852,718  3,853,377

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The protein

Protein family

• [wiki|peptidase M50B family] (according to UniProt)

Structure

• [PDB|3B4R] (from Methanocaldococcus jannaschii, corresponds to aa 15 ... 166, 30% identity) [pubmed|18063795]
• [AF|P70995]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|7CBBC3649B7E37AC33A018C23085748AA6CA1121|ywhC]-[gene|52EB06F920EC02FD32FDE18DD4202E30D5EC8262|ywhD]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A518 (ywhC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/518 NBRP B. subtilis, Japan]
• BKE37530 ([gene|7CBBC3649B7E37AC33A018C23085748AA6CA1121|ywhC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37530 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGTGAGATATCCCTCTTT,  downstream forward: _UP4_CCGCTTTTGTAGGAGGTAGA
• BKK37530 ([gene|7CBBC3649B7E37AC33A018C23085748AA6CA1121|ywhC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37530 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGTGAGATATCCCTCTTT,  downstream forward: _UP4_CCGCTTTTGTAGGAGGTAGA

References

Reviews

• 34410368

Original Publications

• 18063795