Difference between revisions of "MtrB"

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(Expression and regulation)
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 225 bp, 75 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 225 bp, 75 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hepS]]'', ''[[mtrA]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hepS]]'', ''[[folE]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14193&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14193&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[mtrA]]-[[mtrB]]'' {{PubMed|2123343}}  
+
* '''Operon:''' ''[[folE]]-[[mtrB]]'' {{PubMed|2123343}}  
  
 
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2123343}}
 
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2123343}}

Revision as of 19:45, 29 October 2009

  • Description: tryptophan operon RNA-binding attenuation protein (TRAP)

Gene name mtrB
Synonyms
Essential no
Product tryptophan operon RNA-binding attenuation protein (TRAP)
Function regulation of tryptophan biosynthesis
(and translation) attenuation in the trp operon;
repression of the folate operon
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp, Folate
MW, pI 8 kDa, 7.333
Gene length, protein length 225 bp, 75 aa
Immediate neighbours hepS, folE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MtrB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU22770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: prpD family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes controlled by MtrB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 2ZD0 (mutant TRAP, Geobacillus stearothermophilus), 1WAP (complex with L-tryptophan), 2ZP9 (complex with RtpA)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References