RodA

• Description: control of cell shape and elongation
  
  

Gene name	rodA
Synonyms	ywcF, ipa-42d
Essential	yes PubMed
Product	SEDS protein
Function	control of cell shape and elongation
MW, pI	43 kDa, 8.759
Gene length, protein length	1179 bp, 393 aa
Immediate neighbours	nfrA, ywcE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38120

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

cell shape, cell envelope stress proteins (controlled by SigM, W, X, Y), essential genes

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)

• Paralogous protein(s): FtsW, SpoVE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39604

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rodA PubMed

• Sigma factor: SigM Pubmed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Charles Moran, Emory University, NC, USA homepage

References

Gonçalo Real, Allison Fay, Avigdor Eldar, Sérgio M Pinto, Adriano O Henriques, Jonathan Dworkin
Determinants for the subcellular localization and function of a nonessential SEDS protein.
J Bacteriol: 2008, 190(1);363-76
[PubMed:17981970] [WorldCat.org] [DOI] (I p)

A O Henriques, P Glaser, P J Piggot, C P Moran
Control of cell shape and elongation by the rodA gene in Bacillus subtilis.
Mol Microbiol: 1998, 28(2);235-47
[PubMed:9622350] [WorldCat.org] [DOI] (P p)