Difference between revisions of "RecN"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[DNA repair/ recombination]]}},
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{{SubtiWiki category|[[membrane proteins]]}}
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= This gene is a member of the following [[regulons]] =
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=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[DNA repair/ recombination]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 21:13, 8 December 2010

  • Description: DNA repair and genetic recombination

Gene name recN
Synonyms
Essential no
Product unknown
Function DNA repair and genetic recombination
MW, pI 64 kDa, 4.802
Gene length, protein length 1728 bp, 576 aa
Immediate neighbours spoIVB, ahrC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RecN context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

DNA repair/ recombination, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU24240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: recN family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: forespore intermembrane space (according to Swiss-Prot), Nucleoid (Multiple) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References

Reviews

Peter L Graumann, Tobias Knust
Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair.
Chromosome Res: 2009, 17(2);265-75
[PubMed:19308706] [WorldCat.org] [DOI] (I p)

Original publications

Dawit Kidane, Begoña Carrasco, Candela Manfredi, Katharina Rothmaier, Silvia Ayora, Serkalem Tadesse, Juan C Alonso, Peter L Graumann
Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells.
PLoS Genet: 2009, 5(9);e1000630
[PubMed:19730681] [WorldCat.org] [DOI] (I p)

Lyle A Simmons, Alexi I Goranov, Hajime Kobayashi, Bryan W Davies, Daniel S Yuan, Alan D Grossman, Graham C Walker
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction.
J Bacteriol: 2009, 191(4);1152-61
[PubMed:19060143] [WorldCat.org] [DOI] (I p)

Humberto Sanchez, Paula P Cardenas, Shige H Yoshimura, Kunio Takeyasu, Juan C Alonso
Dynamic structures of Bacillus subtilis RecN-DNA complexes.
Nucleic Acids Res: 2008, 36(1);110-20
[PubMed:17999999] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Humberto Sanchez, Dawit Kidane, M Castillo Cozar, Peter L Graumann, Juan C Alonso
Recruitment of Bacillus subtilis RecN to DNA double-strand breaks in the absence of DNA end processing.
J Bacteriol: 2006, 188(2);353-60
[PubMed:16385024] [WorldCat.org] [DOI] (P p)

Humberto Sanchez, Juan C Alonso
Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP.
Nucleic Acids Res: 2005, 33(7);2343-50
[PubMed:15849320] [WorldCat.org] [DOI] (I e)

B E Van Hoy, J A Hoch
Characterization of the spoIVB and recN loci of Bacillus subtilis.
J Bacteriol: 1990, 172(3);1306-11
[PubMed:2106508] [WorldCat.org] [DOI] (P p)