Difference between revisions of "GerD"

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=References=
 
=References=
 
'''Additional references:''' {{PubMed|21398556}}
 
'''Additional references:''' {{PubMed|21398556}}
<pubmed>1906867,19332816,17122337, ,18556788, 19332816 2517635 21696470 </pubmed>
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<pubmed>1906867,19332816,17122337, 21725007,18556788, 19332816 2517635 21696470 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 07:14, 5 July 2011

  • Description: required for clustering of germinant receptors in the spore inner membrane

Gene name gerD
Synonyms
Essential no
Product lipoprotein
Function germination
MW, pI 20 kDa, 4.862
Gene length, protein length 555 bp, 185 aa
Immediate neighbours salA, kbaA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GerD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon

The gene

Basic information

  • Locus tag: BSU01550

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: required for clustering of germinant receptors in the spore inner membrane PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • spore inner membrane PubMed
    • inner spore membrane, spore coat, cortex, germ cell wall, some GerD is also present in the soluble fraction PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:

Labs working on this gene/protein

Anne Moir, University of Sheffield, UK

Your additional remarks

References

Additional references: PubMed

Xuan Yi, Jintao Liu, James R Faeder, Peter Setlow
Synergism between different germinant receptors in the germination of Bacillus subtilis spores.
J Bacteriol: 2011, 193(18);4664-71
[PubMed:21725007] [WorldCat.org] [DOI] (I p)

Keren K Griffiths, Jingqiao Zhang, Ann E Cowan, Ji Yu, Peter Setlow
Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster.
Mol Microbiol: 2011, 81(4);1061-77
[PubMed:21696470] [WorldCat.org] [DOI] (I p)

Wiyada Mongkolthanaruk, Carl Robinson, Anne Moir
Localization of the GerD spore germination protein in the Bacillus subtilis spore.
Microbiology (Reading): 2009, 155(Pt 4);1146-1151
[PubMed:19332816] [WorldCat.org] [DOI] (P p)

Patricia L Pelczar, Peter Setlow
Localization of the germination protein GerD to the inner membrane in Bacillus subtilis spores.
J Bacteriol: 2008, 190(16);5635-41
[PubMed:18556788] [WorldCat.org] [DOI] (I p)

Patricia L Pelczar, Takao Igarashi, Barbara Setlow, Peter Setlow
Role of GerD in germination of Bacillus subtilis spores.
J Bacteriol: 2007, 189(3);1090-8
[PubMed:17122337] [WorldCat.org] [DOI] (P p)

E H Kemp, R L Sammons, A Moir, D Sun, P Setlow
Analysis of transcriptional control of the gerD spore germination gene of Bacillus subtilis 168.
J Bacteriol: 1991, 173(15);4646-52
[PubMed:1906867] [WorldCat.org] [DOI] (P p)

J R Yon, R L Sammons, D A Smith
Cloning and sequencing of the gerD gene of Bacillus subtilis.
J Gen Microbiol: 1989, 135(12);3431-45
[PubMed:2517635] [WorldCat.org] [DOI] (P p)