Difference between revisions of "MtlA"
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| − | + | * '''Description:''' [[trigger enzymes|trigger enzyme]]: mannitol-specific [[PTS|phosphotransferase system]], EIICB of the [[PTS]]<br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || mannitol uptake and phosphorylation, control of [[MtlR]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || mannitol uptake and phosphorylation, control of [[MtlR]] activity | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/MtlA MtlA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/MtlA MtlA] | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:mtlA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mtlA_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' ''[[mtlA]]-[[mtlF]]-[[mtlD]]'' {{PubMed|12897001}} | * '''Operon:''' ''[[mtlA]]-[[mtlF]]-[[mtlD]]'' {{PubMed|12897001}} | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|22014119}} |
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* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 11:23, 7 August 2012
- Description: trigger enzyme: mannitol-specific phosphotransferase system, EIICB of the PTS
| Gene name | mtlA |
| Synonyms | |
| Essential | no |
| Product | trigger enzyme: mannitol-specific phosphotransferase system, EIICB |
| Function | mannitol uptake and phosphorylation, control of MtlR activity |
| Interactions involving this protein in SubtInteract: MtlA | |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 50 kDa, 8.814 |
| Gene length, protein length | 1434 bp, 478 aa |
| Immediate neighbours | ycnL, mtlF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
phosphotransferase systems, utilization of specific carbon sources, transcription factors and their control, trigger enzyme, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03981
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-559 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: P42956
- KEGG entry: [3]
- E.C. number: 2.7.1.69
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
