Difference between revisions of "YcbC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of D-glucarate/galactarate
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of D-glucarate/galactarate
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02460 ycbC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02460 ycbC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.375   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.375   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glnL]]'', ''[[ycbD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glnL]]'', ''[[ycbD]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12040&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02460 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02460 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02460 Advanced_DNA]
 
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Revision as of 12:03, 13 May 2013

  • Description: 5-dehydro-4-deoxyglucarate dehydratase

Gene name ycbC
Synonyms
Essential no
Product 5-dehydro-4-deoxyglucarate dehydratase
Function utilization of D-glucarate/galactarate
Gene expression levels in SubtiExpress: ycbC
MW, pI 33 kDa, 5.375
Gene length, protein length 924 bp, 308 aa
Immediate neighbours glnL, ycbD
Sequences Protein DNA Advanced_DNA
Genetic context
YcbC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YcbC expression.png
























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

YcbG regulon

The gene

Basic information

  • Locus tag: BSU02460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2 (according to Swiss-Prot)
  • Protein family: DHDPS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induced by D-glucarate/galactarate (YcbG) PubMed
  • Regulatory mechanism: YcbG: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Shigeo Hosoya, Kunio Yamane, Michio Takeuchi, Tsutomu Sato
Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.
FEMS Microbiol Lett: 2002, 210(2);193-9
[PubMed:12044674] [WorldCat.org] [DOI] (P p)