Difference between revisions of "ComGC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24710 comGC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24710 comGC]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGC ComGC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGC ComGC]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGD]]'', ''[[comGB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGD]]'', ''[[comGB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14402&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24710 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:comGC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:comGC_context.gif]]

Revision as of 13:17, 13 May 2013

  • Description: DNA uptake, major component of the pseudopilus

Gene name comGC
Synonyms
Essential no
Product major pseudopilin
Function genetic competence
Gene expression levels in SubtiExpress: comGC
Interactions involving this protein in SubtInteract: ComGC
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 10 kDa, 6.325
Gene length, protein length 294 bp, 98 aa
Immediate neighbours comGD, comGB
Sequences Protein DNA Advanced_DNA
Genetic context
ComGC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComGC expression.png
























Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU24710

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: comGC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell surface PubMed
    • localizes to the cell membrane and the cytoplasm PubMed
    • localizes to one single cell pole in the majority of the cells PubMed

= Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159] [WorldCat.org] [DOI] (P p)

Original publications