Difference between revisions of "YaaT"
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Revision as of 12:17, 16 May 2013
- Description: control of the phosphorelay, required for the achieving a sufficient level of Spo0A-P for sporulation initiation
| Gene name | yaaT |
| Synonyms | |
| Essential | no |
| Product | part of the YaaT-YmcA-YlbF complex |
| Function | regulation of sporulation initiation |
| Gene expression levels in SubtiExpress: yaaT | |
| Interactions involving this protein in SubtInteract: YaaT | |
| MW, pI | 31 kDa, 4.838 |
| Gene length, protein length | 825 bp, 275 aa |
| Immediate neighbours | holB, yabA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
phosphorelay, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00320
Phenotypes of a mutant
- block of sporulation at stage 0 PubMed
- strongly reduced genetic competence, strongly reduced sporulation PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- peripheral membrane, as well as to the septum, during sporulation PubMed
Database entries
- Structure:
- UniProt: P37541
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- expressed during growth and the transition phase, expression is erduced in stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Valerie J Carabetta, Andrew W Tanner, Todd M Greco, Melissa Defrancesco, Ileana M Cristea, David Dubnau
A complex of YlbF, YmcA and YaaT regulates sporulation, competence and biofilm formation by accelerating the phosphorylation of Spo0A.
Mol Microbiol: 2013, 88(2);283-300
[PubMed:23490197]
[WorldCat.org]
[DOI]
(I p)
Shigeo Hosoya, Kei Asai, Naotake Ogasawara, Michio Takeuchi, Tsutomu Sato
Mutation in yaaT leads to significant inhibition of phosphorelay during sporulation in Bacillus subtilis.
J Bacteriol: 2002, 184(20);5545-53
[PubMed:12270811]
[WorldCat.org]
[DOI]
(P p)
