Difference between revisions of "Tgl"
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| − | * '''Description:''' spore associated transglutaminase <br/><br/> | + | * '''Description:''' outer spore coat protein, spore associated transglutaminase <br/><br/> |
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigE regulon]]}}, | ||
{{SubtiWiki regulon|[[SigK regulon]]}} | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
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=== Additional information=== | === Additional information=== | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** outer spore coat, localization depends on [[CotE]] {{PubMed|22171814}} | ||
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tgl_3212591_3213328_1 tgl] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tgl_3212591_3213328_1 tgl] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigK]] {{PubMed|15699190,12501297}} | + | * '''Sigma factor:''' [[SigK]] {{PubMed|15699190,12501297}}, SigE |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|15699190,12501297}} | + | ** expressed late during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]]) {{PubMed|15383836,15699190,12501297}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** GerE: transcription repression {{PubMed|15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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<pubmed>19797877 </pubmed> | <pubmed>19797877 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>18249137,,12501297,16267299,11193401, 16751597 9274030 15699190</pubmed> | + | <pubmed>18249137, 22171814,12501297,16267299,11193401, 16751597 9274030 15699190 15383836 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:36, 13 August 2013
- Description: outer spore coat protein, spore associated transglutaminase
| Gene name | tgl |
| Synonyms | yuxF, yugV |
| Essential | no |
| Product | spore associated transglutaminase |
| Function | introduction of crosslinks in the spore coat protein GerQ |
| Gene expression levels in SubtiExpress: tgl | |
| MW, pI | 28 kDa, 6.687 |
| Gene length, protein length | 735 bp, 245 aa |
| Immediate neighbours | mcpB, yuzH |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
GerE regulon, SigE regulon, SigK regulon
The gene
Basic information
- Locus tag: BSU31270
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3 (according to Swiss-Prot), temperature-dependent modification of the coat proteins such as GerQ (together with YabG) PubMed
- Protein family: bacillus TGase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P40746
- KEGG entry: [3]
- E.C. number: 2.3.2.13
Additional information
Expression and regulation
- Regulatory mechanism:
- GerE: transcription repression PubMed
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Adriano Henriques, Lisbon, Portugal homepage
Your additional remarks
References
Reviews
Ritsuko Kuwana
[Protein modification system in dormant cells].
Yakugaku Zasshi: 2009, 129(10);1221-5
[PubMed:19797877]
[WorldCat.org]
[DOI]
(P p)
Original Publications
