Difference between revisions of "FadR"

From SubtiWiki
Jump to: navigation, search
Line 62: Line 62:
  
 
=== Additional information===
 
=== Additional information===
 
 
  
  
Line 80: Line 78:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
* '''Effectors of protein activity:''' long chain fatty acids act as inducers that release FadR from its operator sites
+
* '''Effectors of protein activity:''' long chain fatty acids act as inducers that release FadR from its operator sites {{PubMed|24356978}}
  
 
* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
Line 148: Line 146:
 
<pubmed>17919287, 24006471 </pubmed>
 
<pubmed>17919287, 24006471 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>17189250,21398533</pubmed>
+
<pubmed>17189250,21398533 24356978</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:23, 27 December 2013

  • Description: transcriptional repressor (TetR family), regulation of fatty acid degradation

Gene name fadR
Synonyms ysiA
Essential no
Product transcriptional repressor
Function regulation of fatty acid degradation
Gene expression levels in SubtiExpress: fadR
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 21 kDa, 6.118
Gene length, protein length 582 bp, 194 aa
Immediate neighbours fadB, lcfA
Sequences Protein DNA DNA_with_flanks
Genetic context
YsiA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadR expression.png















Categories containing this gene/protein

utilization of lipids, transcription factors and their control

This gene is a member of the following regulons

CcpA regulon, FadR regulon

The FadR regulon

The gene

Basic information

  • Locus tag: BSU28550

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity: long chain fatty acids act as inducers that release FadR from its operator sites PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Leslie Cuthbertson, Justin R Nodwell
The TetR family of regulators.
Microbiol Mol Biol Rev: 2013, 77(3);440-75
[PubMed:24006471] [WorldCat.org] [DOI] (I p)

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)

Original publications