Difference between revisions of "SigI"

From SubtiWiki
Jump to: navigation, search
(References)
Line 147: Line 147:
 
=References=
 
=References=
  
<pubmed>19114499,17185538,11157964 18156261, 21541672 24125693</pubmed>
+
<pubmed>19114499,17185538,11157964 18156261, 21541672 24125693 23199363</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:25, 28 December 2013

Gene name sigI
Synonyms ykoZ
Essential no
Product RNA polymerase sigma factor SigI
Function control of a class of heat shock genes
Gene expression levels in SubtiExpress: sigI
Interactions involving this protein in SubtInteract: SigI
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 29 kDa, 8.306
Gene length, protein length 753 bp, 251 aa
Immediate neighbours ykoY, rsgI
Sequences Protein DNA DNA_with_flanks
Genetic context
SigI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SigI expression.png















Categories containing this gene/protein

transcription, sigma factors and their control, heat shock proteins

This gene is a member of the following regulons

SigI regulon, WalR regulon

The SigI regulon: bcrC, gsiB, lytE, mreBH, sigI-rsgI

The gene

Basic information

  • Locus tag: BSU13450

Phenotypes of a mutant

  • temperature-sensitive growth on agar plates PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

overexpression of SigI suppresses mreB mreBH mbl mutants PubMed

Expression and regulation

  • Regulatory mechanism:


  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Wan-Zhen Huang, Jyun-Jhih Wang, Hui-Ju Chen, Jung-Tze Chen, Gwo-Chyuan Shaw
The heat-inducible essential response regulator WalR positively regulates transcription of sigI, mreBH and lytE in Bacillus subtilis under heat stress.
Res Microbiol: 2013, 164(10);998-1008
[PubMed:24125693] [WorldCat.org] [DOI] (I p)

Letal I Salzberg, Leagh Powell, Karsten Hokamp, Eric Botella, David Noone, Kevin M Devine
The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control CwlO and LytE expression in exponentially growing and stressed Bacillus subtilis cells.
Mol Microbiol: 2013, 87(1);180-95
[PubMed:23199363] [WorldCat.org] [DOI] (I p)

Chi-Ling Tseng, Jung-Tze Chen, Ju-Hui Lin, Wan-Zhen Huang, Gwo-Chyuan Shaw
Genetic evidence for involvement of the alternative sigma factor SigI in controlling expression of the cell wall hydrolase gene lytE and contribution of LytE to heat survival of Bacillus subtilis.
Arch Microbiol: 2011, 193(9);677-85
[PubMed:21541672] [WorldCat.org] [DOI] (I p)

Kathrin Schirner, Jeff Errington
The cell wall regulator {sigma}I specifically suppresses the lethal phenotype of mbl mutants in Bacillus subtilis.
J Bacteriol: 2009, 191(5);1404-13
[PubMed:19114499] [WorldCat.org] [DOI] (I p)

Chi-Ling Tseng, Gwo-Chyuan Shaw
Genetic evidence for the actin homolog gene mreBH and the bacitracin resistance gene bcrC as targets of the alternative sigma factor SigI of Bacillus subtilis.
J Bacteriol: 2008, 190(5);1561-7
[PubMed:18156261] [WorldCat.org] [DOI] (I p)

Kei Asai, Takafumi Ootsuji, Kazue Obata, Takashi Matsumoto, Yasutaro Fujita, Yoshito Sadaie
Regulatory role of RsgI in sigI expression in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 1);92-101
[PubMed:17185538] [WorldCat.org] [DOI] (P p)

U Zuber, K Drzewiecki, M Hecker
Putative sigma factor SigI (YkoZ) of Bacillus subtilis is induced by heat shock.
J Bacteriol: 2001, 183(4);1472-5
[PubMed:11157964] [WorldCat.org] [DOI] (P p)