Difference between revisions of "FadH"
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14060 fadH] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14060 fadH] | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=fadH fadH]''' |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 6.495 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 6.495 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuE]]'', ''[[fadG]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuE]]'', ''[[fadG]]'' | ||
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| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14060 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14060 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14060 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14060 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14060 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14060 DNA_with_flanks] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykuF_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ykuF_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fadH_1478072_1478836_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:fadH_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fadH_1478072_1478836_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:fadH_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14060]] |
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|} | |} | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU14060&redirect=T BSU14060] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ykuFG.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ykuFG.html] | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU14060&redirect=T BSU14060] | ||
* '''Structure:''' | * '''Structure:''' | ||
Latest revision as of 13:34, 2 April 2014
- Description: 2,4-dienoyl-CoA reductase
| Gene name | fadH |
| Synonyms | ykuF |
| Essential | no |
| Product | 2,4-dienoyl-CoA reductase |
| Function | fatty acid degradation |
| Gene expression levels in SubtiExpress: fadH | |
| Metabolic function and regulation of this protein in SubtiPathways: fadH | |
| MW, pI | 26 kDa, 6.495 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | ykuE, fadG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14060
Phenotypes of a mutant
Database entries
- BsubCyc: BSU14060
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH (according to Swiss-Prot)
- Protein family: 2,4-dienoyl-CoA reductase subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU14060
- Structure:
- UniProt: O34717
- KEGG entry: [3]
- E.C. number: 1.3.1.34
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287]
[WorldCat.org]
[DOI]
(P p)
Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250]
[WorldCat.org]
[DOI]
(P p)
