Difference between revisions of "FsrA"

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|''fsrA''
 
|''fsrA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''mrgC''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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<br/><br/>
 
<br/><br/>
 +
 +
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[carbon core metabolism]]}},
 +
{{SubtiWiki category|[[acquisition of iron]]}},
 +
{{SubtiWiki category|[[ncRNA]]}}
 +
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[Fur regulon]]}}
 +
=The [[FsrA regulon]]''=
  
 
=The gene=
 
=The gene=
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* transcription profile of a ''[[fsrA]]'' mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
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* '''SubtiList entry:''' no entry
 
* '''SubtiList entry:''' no entry
  
* '''Structure:'''
+
* '''GEO entry:''' [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
 +
 
 +
* '''Structure:'''
  
 
=== Additional information===
 
=== Additional information===
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=== Additional information===
 
=== Additional information===
 +
 +
  
 
=The RNA=
 
=The RNA=
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs and inhibits their translation. [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
+
* '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[sdhC]], [[citB]], [[lutB]], [[gltA]]-[[gltB]]'', and ''[[leuC]]-[[leuD]]'' mRNAs and inhibits their translation. {{PubMed|18697947,22389480}}
  
 
=== Extended information on the RNA===
 
=== Extended information on the RNA===
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* '''Kinetic information'''
 
* '''Kinetic information'''
  
* '''Interactions:''' Binds ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
+
* '''[[SubtInteract|Interactions]]:'''
 +
** Binds ''[[sdhC]], [[citB]], [[lutB]], [[gltA]]-[[gltB]]'', and ''[[leuC]]-[[leuD]]'' mRNAs {{PubMed|18697947,22389480}}
  
* '''Localization'''
+
* '''[[Localization]]'''
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
  
 
* '''Structure''':  
 
* '''Structure''':  
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=References=
 
=References=
  
<pubmed>18697947,,18697947, </pubmed>
+
<pubmed>22427629,18697947,22389480</pubmed>
# Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD (2008) The ''Bacillus subtilis'' iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. PNAS 105: 11927-11932. [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
+
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
+
[[Category:small RNA]]

Latest revision as of 15:23, 2 April 2014

  • Description: regulatory RNA

Gene name fsrA
Synonyms
Essential no
Product sRNA FsrA
Function inhibition of sdhC translation
Gene length aaa bp
Immediate neighbours ykuI, ykuJ
Gene sequence (+200bp)
Genetic context
FsrA context.jpg



Categories containing this gene/protein

carbon core metabolism, acquisition of iron, ncRNA

This gene is a member of the following regulons

Fur regulon

The FsrA regulon

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • BsubCyc: ?
  • BsubCyc: ?
  • DBTBS entry: no entry
  • SubtiList entry: no entry
  • Structure:

Additional information

  • Swiss prot entry:
  • KEGG entry: no entry
  • E.C. number:

Additional information

The RNA

Basic information/ Evolution

Extended information on the RNA

  • Kinetic information

Database entries

  • BsubCyc: ?
  • BsubCyc: ?
  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation: induced by iron starvation (Fur) PubMed
  • Regulatory mechanism: Fur: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:

Labs working on this gene/RNA

John Helmann, Cornell University, USA Homepage

Your additional remarks

References