Difference between revisions of "Sfp/1"

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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:'''
+
* '''Protein family:''' Gsp/sfp/hetI/acpT family (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''

Revision as of 19:17, 7 May 2009

  • Description: phosphopantetheinyl transferase, inactive pseudogene in strain 168

Gene name sfp
Synonyms
Essential no
Product phosphopantetheinyl transferase
Function phosphopantetheinylates a serine residue in each of the

seven peptidyl carrier protein domains

of the first three subunits of surfactin synthetase (SrfABC)

MW, pI 19 kDa, 8.38
Gene length, protein length 495 bp, 165 aa
Immediate neighbours ycxD, yczE
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
Sfp context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

No swarming motility on B medium. PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

This gene is a pseudogene in B. subtilis 168 due to a mutation that resulted in an internal frameshift. The second part of the pseudogene is sfp/2.

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Gsp/sfp/hetI/acpT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1QR0 (complex with CoA)
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks

References

  1. Hamze et al. (2009) Identification of genes required for different stages of dendritic swarming in Bacillus subtilis, with a novel role for phrC. Microbiology 155: 398-412. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed