RsbV

• Description: anti-anti-SigB, antagonist of RsbW
  
  

Gene name	rsbV
Synonyms
Essential	no
Product	anti-anti-SigB
Function	control of SigB activity
MW, pI	11 kDa, 4.698
Gene length, protein length	327 bp, 109 aa
Immediate neighbours	rsbU, rsbW
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: STAS domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on Ser-52 AND Ser-56 OR Thr-57 PubMed, PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RsbU-RsbV, RsbV-SpoIIAB, RsbV-RsbW, RsbW PubMed

• Localization:

Database entries

• Structure: 1VC1 (homolog from Thermotoga maritima)

• Swiss prot entry: P17903

• KEGG entry: BSU04710

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Eymann et al. (2007) Dynamics of protein phosphorylation on Ser/Thr/Tyr in Bacillus subtilis. Proteomics 7: 3509-3526. PubMed
2. Petersohn et al. (2001) Global Analysis of the General Stress Response of Bacillus subtilis. J Bacteriol. 183: 5617-5631 PubMed
3. Macek et al. (2007) The serine/ threonine/ tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6: 697-707 PubMed
4. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed