Difference between revisions of "DnaJ"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[hrcA]]-[[grpE]]-[[dnaK]]-[[dnaJ]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/1339421 PubMed]
+
''[[hrcA]]-[[grpE]]-[[dnaK]]-[[dnaJ]]-[[yqeT]]-[[yqeU]]-[[yqeV]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9023197 PubMed]
  
 
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1339421 PubMed]
 
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1339421 PubMed]
  
* '''Regulation:''' induced by heat shock [http://www.ncbi.nlm.nih.gov/sites/entrez/1339421 PubMed]
+
* '''Regulation:''' induced by heat shock ([[HrcA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/1339421 PubMed]
  
 
* '''Regulatory mechanism:''' repressed at normal temperature by [[HrcA]]
 
* '''Regulatory mechanism:''' repressed at normal temperature by [[HrcA]]

Revision as of 21:10, 30 May 2009

  • Description: heat-shock protein (activation of DnaK)

Gene name dnaJ
Synonyms
Essential no
Product heat-shock protein (activation of DnaK)
Function protein quality control
MW, pI 40 kDa, 7.92
Gene length, protein length 1116 bp, 372 aa
Immediate neighbours yqeT, surC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DnaJ context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dnaJ family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

hrcA-grpE-dnaK-dnaJ-yqeT-yqeU-yqeV PubMed

  • Regulatory mechanism: repressed at normal temperature by HrcA
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Wolfgang Schumann, Bayreuth University, Germany Homepage

Your additional remarks

References

  1. Wetzstein, M., U. Völker, J. Dedio, S. Löbau, U. Zuber, M. Schiesswohl, C. Herget, M. Hecker, and W. Schumann. 1992. Cloning, sequencing, and molecular analysis of the dnaK locus from Bacillus subtilis. J. Bacteriol. 174:3300-3310. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed