Difference between revisions of "CccA"

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(Expression and regulation)
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=== Basic information ===
 
=== Basic information ===
  
* '''Coordinates:'''
+
* '''Locus tag:'''
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 23:40, 2 June 2009

  • Description: cytochrome c550

Gene name cccA
Synonyms
Essential no
Product cytochrome c550
Function respiration
MW, pI 12 kDa, 5.276
Gene length, protein length 360 bp, 120 aa
Immediate neighbours yqfN, sigA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CccA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (4.8-fold) (CcpA) PubMed, carbon catabolite repression (CcpA) PubMed
  • Regulatory mechanism: CcpA: transcription repression, CcpA: transcription repression, cre site overlaps -35 region of the promoter PubMed
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
  2. Monedero, V., Boël, G., and Deutscher, J. (2001). Catabolite regulation of the cytochrome c550-encoding Bacillus subtilis cccA gene. J. Mol. Microbiol. Biotechnol. 3, 433-438. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed