Difference between revisions of "Sandbox"

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* '''Description:''' component of the TatAdCd twin-arginine translocase<br/><br/>
+
* '''Description:''' thioredoxin-like protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''tatAD''
+
|''tlp''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yczB ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || component of the twin-arginine <br>translocation pathway
+
|style="background:#ABCDEF;" align="center"| '''Product''' || thioredoxin-like protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || protein secretion
+
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 7 kDa, 9.693  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.439  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 210 bp, 70 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 249 bp, 83 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phoD]]'', ''[[tatCD]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nucA]]'', ''[[hxlB]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12057&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13686&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|-
+
|colspan="2" | '''Genetic context''' <br/> [[Image:tlp_context.gif]]
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:tatAD_context.gif]]
 
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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__TOC__
 
__TOC__
  
<br/><br/><br/><br/>
+
<br/><br/>
  
 
=The gene=
 
=The gene=
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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:''' BSU02630
+
* '''Locus tag:''' BSU18030
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' no entry
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sspN-tlp.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12777]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11806]
  
 
=== Additional information===
 
=== Additional information===
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' translocation of [[PhoD]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
+
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' tatA/E family (according to Swiss-Prot)
+
* '''Protein family:''' tlp family (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[TatAD]]-[[PhoD]],  [[TatAD]]-[[TatCD]], [[TatAD]]-[[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
+
* '''Interactions:'''
  
* '''Localization:''' membrane (according to Swiss-Prot),  forms foci at the division sites and cell poles, localization requires interaction with [[TatCD]] or [[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
+
* '''Localization:''' spore core (according to Swiss-Prot)
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Structure:'''
 
* '''Structure:'''
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O31467 O31467]
+
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/Q45060 Q45060]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU02630]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU18030]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 90: Line 88:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[sspN]]-[[tlp]]''
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
Line 115: Line 113:
  
 
=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 
[[Oscar Kuipers]], University of Groningen, The Netherlands
 
[http://molgen.biol.rug.nl/molgen/index.php Homepage]
 
  
 
=Your additional remarks=
 
=Your additional remarks=
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=References=
 
=References=
  
<pubmed> 19395490 </pubmed>
 
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 19:17, 7 June 2009

  • Description: thioredoxin-like protein

Gene name tlp
Synonyms
Essential no
Product thioredoxin-like protein
Function unknown
MW, pI 9 kDa, 4.439
Gene length, protein length 249 bp, 83 aa
Immediate neighbours nucA, hxlB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Tlp context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18030

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: tlp family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: spore core (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed