Difference between revisions of "CoaA"

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(Expression and regulation)
(Database entries)
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1SQ5 1SQ5] (from ''Escherichia coli'', 49% identity, 67% similarity) {{PubMed|15136582}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P54556 P54556]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P54556 P54556]

Revision as of 12:31, 18 February 2010

  • Description: probable pantothenate kinase

Gene name coaA
Synonyms yqjS
Essential no
Product probable pantothenate kinase
Function biosynthesis of coenzyme A
Metabolic function and regulation of this protein in SubtiPathways:
Coenzyme A
MW, pI 36 kDa, 5.894
Gene length, protein length 957 bp, 319 aa
Immediate neighbours yqjT, dsdA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CoaA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU23760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate (according to Swiss-Prot)
  • Protein family: prokaryotic pantothenate kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1SQ5 (from Escherichia coli, 49% identity, 67% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

W J Song, S Jackowski
Cloning, sequencing, and expression of the pantothenate kinase (coaA) gene of Escherichia coli.
J Bacteriol: 1992, 174(20);6411-7
[PubMed:1328157] [WorldCat.org] [DOI] (P p)