Difference between revisions of "CzcD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cation efflux, resistence against Zn, Cu, Co, Ni
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cation efflux, resistence against Zn, Cu, Co, Ni
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://cellpublisher.gobics.de/view/GqbblRJkBH metal ion homeostasis]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 5.859   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 5.859   

Revision as of 22:03, 10 March 2011

  • Description: cation diffusion facilitator

Gene name czcD
Synonyms yrdO
Essential no
Product cation diffusion facilitator
Function cation efflux, resistence against Zn, Cu, Co, Ni
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 34 kDa, 5.859
Gene length, protein length 933 bp, 311 aa
Immediate neighbours trkA, yrdN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CzcD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), resistance against toxic metals, membrane proteins

This gene is a member of the following regulons

CzrA regulon

The gene

Basic information

  • Locus tag: BSU26650

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) (CzrA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Charles M Moore, Ahmed Gaballa, Monica Hui, Rick W Ye, John D Helmann
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Mol Microbiol: 2005, 57(1);27-40
[PubMed:15948947] [WorldCat.org] [DOI] (P p)