Difference between revisions of "MurF"

From SubtiWiki
Jump to: navigation, search
Line 40: Line 40:
 
=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU04570
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
Line 87: Line 87:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P96613 P96613]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P96613 P96613]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU04570 BSU04570]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU04570]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.2.10 6.3.2.10]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.2.10 6.3.2.10]

Revision as of 14:00, 3 June 2009

  • Description: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase

Gene name murF
Synonyms ydbQ
Essential yes PubMed
Product UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-
2,6- diaminopimeloyl-D-alanyl-D-alanine synthetase
Function peptidoglycan precursor biosynthesis
MW, pI 49 kDa, 5.337
Gene length, protein length 1371 bp, 457 aa
Immediate neighbours ddl, cshA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MurF context.gif
This image was kindly provided by SubtiList






The gene

Basic information

  • Locus tag: BSU04570

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine (according to Swiss-Prot)
  • Protein family: murCDEF family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed