RluB

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  • Description: pseudouridine synthase

Gene name rluB
Synonyms ypuL
Essential no
Product pseudouridine synthase
Function 23S rRNA modification
MW, pI 25 kDa, 10.253
Gene length, protein length 687 bp, 229 aa
Immediate neighbours resA, spmB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RluB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU23160

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: rRNA uridine = rRNA pseudouridine (according to Swiss-Prot)
  • Protein family: pseudouridine synthase rsuA family (according to Swiss-Prot)
  • Paralogous protein(s): YtzF

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

L Niu, B G Lane, J Ofengand
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.
Biochemistry: 1999, 38(2);629-35
[PubMed:9888802] [WorldCat.org] [DOI] (P p)