FtsA

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  • Description: cell-division protein, membrane anchor for FtsZ

Gene name ftsA
Synonyms spoIIN
Essential yes PubMed
Product cell-division protein
Function formation of Z-ring
MW, pI 47 kDa, 5.094
Gene length, protein length 1320 bp, 440 aa
Immediate neighbours sbp, ftsZ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FtsA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell division, essential genes, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SigH regulon, WalR regulon

The gene

Basic information

  • Locus tag: BSU15280

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsA/mreB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • septal at the cell membrane PubMed
    • septal localization depends on the proton motive force PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248] [WorldCat.org] [DOI] (I p)

Original Publications