LepA

• Description: GTP-binding protein
  
  

Gene name	lepA
Synonyms	yqxB, yqeQ
Essential	no
Product	GTP-binding protein
Function	unknown
Gene expression levels in SubtiExpress: lepA
MW, pI	68 kDa, 4.984
Gene length, protein length	1836 bp, 612 aa
Immediate neighbours	hemN, yqxA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

GTP-binding proteins

The gene

Basic information

• Locus tag: BSU25510

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LepA subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• UniProt: P37949

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lepA-hemN PubMed

• Expression browser: lepA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

B Hippler, G Homuth, T Hoffmann, C Hungerer, W Schumann, D Jahn
Characterization of Bacillus subtilis hemN.
J Bacteriol: 1997, 179(22);7181-5
[PubMed:9371469] [WorldCat.org] [DOI] (P p)

G Homuth, M Heinemann, U Zuber, W Schumann
The genes of lepA and hemN form a bicistronic operon in Bacillus subtilis.
Microbiology (Reading): 1996, 142 ( Pt 7);1641-9
[PubMed:8757728] [WorldCat.org] [DOI] (P p)