PhrH

Gene name	phrH
Synonyms
Essential	no
Product	secreted regulator of the activity of phosphatase RapH
Function	control of sporulation initiation
Gene expression levels in SubtiExpress: phrH
Interactions involving this protein in SubtInteract: PhrH
MW, pI
Gene length, protein length
Immediate neighbours	rapH, yeeI
Gene sequence (+200bp)	Protein sequence
Genetic context File:PhrH context.gif
[None Expression at a glance]   PubMed

Categories containing this gene/protein

phosphorelay, quorum sensing, short peptides

This gene is a member of the following regulons

RghR regulon

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RapH-PhrH PubMed

• Localization:
  • secreted as hexapeptide TDRNTT PubMed, uptake by the (OppD-OppF)-(OppB-OppC)-OppA ABC transporter PubMed

Database entries

• Structure:

• UniProt: Q59HN7

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:
  • rapH-phrH PubMed
  • phrH PubMed

• Sigma factor:
  • rapH: SigA PubMed
  • phrH: SigA PubMed

• Regulation:
  • rapH: repressed by RghR PubMed

• Regulatory mechanism:
  • RghR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publikations: PubMed

Kentaro Hayashi, Tsukahara Kensuke, Kazuo Kobayashi, Naotake Ogasawara, Mitsuo Ogura
Bacillus subtilis RghR (YvaN) represses rapG and rapH, which encode inhibitors of expression of the srfA operon.
Mol Microbiol: 2006, 59(6);1714-29
[PubMed:16553878] [WorldCat.org] [DOI] (P p)