GabP

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  • Description: gamma-amino butyric acid permease

Gene name gabP
Synonyms nrg-21
Essential no
Product gamma-amino butyric acid permease
Function utilization of gamma-amino butyric acid
Gene expression levels in SubtiExpress: gabP
Metabolic function and regulation of this protein in SubtiPathways:
Ala, Gly, Ser
MW, pI 50 kDa, 9.45
Gene length, protein length 1407 bp, 469 aa
Immediate neighbours cotA, yeaB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GabP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GabP expression.png




























Categories containing this gene/protein

transporters/ other, utilization of amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon, TnrA regulon

The gene

Basic information

  • Locus tag: BSU06310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: View classification (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

A E Ferson, L V Wray, S H Fisher
Expression of the Bacillus subtilis gabP gene is regulated independently in response to nitrogen and amino acid availability.
Mol Microbiol: 1996, 22(4);693-701
[PubMed:8951816] [WorldCat.org] [DOI] (P p)