DnaB

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  • Description: initiation of chromosome replication/ membrane attachment protein, part of the replisome

Gene name dnaB
Synonyms
Essential yes PubMed
Product initiation of chromosome replication/ membrane attachment protein
Function DNA replication
Gene expression levels in SubtiExpress: dnaB
Interactions involving this protein in SubtInteract: DnaB
MW, pI 54 kDa, 5.278
Gene length, protein length 1416 bp, 472 aa
Immediate neighbours dnaI, ytcG
Sequences Protein DNA Advanced_DNA
Genetic context
DnaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DnaB expression.png
























Categories containing this gene/protein

DNA replication, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU28990

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Geoffrey S Briggs, Wiep Klaas Smits, Panos Soultanas
Chromosomal replication initiation machinery of low-G+C-content Firmicutes.
J Bacteriol: 2012, 194(19);5162-70
[PubMed:22797751] [WorldCat.org] [DOI] (I p)

Original publications