YueC

• Description: membrane protein, part of the type VII protein secretion system YukD-YukC-YukB-YueB-YueC
  
  

Gene name	yueC
Synonyms
Essential	no
Product	part of the type VII protein secretion system
Function	export of YukE
Gene expression levels in SubtiExpress: yueC
MW, pI	16 kDa, 4.138
Gene length, protein length	453 bp, 151 aa
Immediate neighbours	yueD, yueB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

• Locus tag: BSU31850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • membrane (according to Swiss-Prot) PubMed

Database entries

• Structure:

• UniProt: O32100

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yukE-yukD-yukC-yukB-yueB-yueC PubMed

• Expression browser: yueC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • not expressed in the lab strain 168, due to lack of DegU-P PubMed
  • expressed in the stationary phase PubMed

• Regulatory mechanism:
  • DegU-P: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Roxane Simeone, Daria Bottai, Roland Brosch
ESX/type VII secretion systems and their role in host-pathogen interaction.
Curr Opin Microbiol: 2009, 12(1);4-10
[PubMed:19155186] [WorldCat.org] [DOI] (I p)

Mark J Pallen
The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system?
Trends Microbiol: 2002, 10(5);209-12
[PubMed:11973144] [WorldCat.org] [DOI] (P p)

Original publications

Catarina Baptista, Hugo Condessa Barreto, Carlos São-José
High levels of DegU-P activate an Esat-6-like secretion system in Bacillus subtilis.
PLoS One: 2013, 8(7);e67840
[PubMed:23861817] [WorldCat.org] [DOI] (I e)

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)