PbpI

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Gene name pbpI
Synonyms yrrR
Essential no
Product penicillin-binding protein 4b
Function unknown
Gene expression levels in SubtiExpress: pbpI
MW, pI 65 kDa, 9.012
Gene length, protein length 1752 bp, 584 aa
Immediate neighbours yrrS, greA
Sequences Protein DNA DNA_with_flanks
Genetic context
YrrR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbpI expression.png
























Categories containing this gene/protein

cell wall synthesis, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigF regulon

The gene

Basic information

  • Locus tag: BSU27310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transpeptidase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

Dirk-Jan Scheffers
Dynamic localization of penicillin-binding proteins during spore development in Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 3);999-1012
[PubMed:15758244] [WorldCat.org] [DOI] (P p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Yuping Wei, Derrell C McPherson, David L Popham
A mother cell-specific class B penicillin-binding protein, PBP4b, in Bacillus subtilis.
J Bacteriol: 2004, 186(1);258-61
[PubMed:14679248] [WorldCat.org] [DOI] (P p)