CheY

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  • Description: two-component response regulator, modulation of flagellar switch bias

Gene name cheY
Synonyms cheB
Essential no
Product two-component response regulator
Function modulation of flagellar switch bias
Gene expression levels in SubtiExpress: cheY
Interactions involving this protein in SubtInteract: CheY
MW, pI 13 kDa, 4.746
Gene length, protein length 360 bp, 120 aa
Immediate neighbours fliY, fliZ
Sequences Protein DNA DNA_with_flanks
Genetic context
CheY context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CheY expression.png















Categories containing this gene/protein

transcription factors and their control, motility and chemotaxis, phosphoproteins

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16330

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YneI

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated by CheA on an Asp residue
    • dephosphorylated by CheC PubMed
  • Effectors of protein activity:

Database entries

  • Structure: 1TMY (CheY from Thermotoga maritima)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium, CheY is present with 7,100 +/- 1,000 molecules per cell PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1164 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 2117 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original Publications