Pta

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  • Description: phosphotransacetylase

Gene name pta
Synonyms ipa-88d, ywfJ
Essential no
Product phosphotransacetylase
Function overflow metabolism
MW, pI 34 kDa, 4.649
Gene length, protein length 969 bp, 323 aa
Immediate neighbours cysL, ywfI
Gene sequence (+200bp) Protein sequence
Genetic context
Pta context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on (Ser-123 OR Thr-128 OR Ser-129) PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation: expression activated by glucose (2.56) (CcpA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
  2. Macek et al. (2007) The serine/ threonine/ tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6: 697-707 PubMed
  3. Presecan-Siedel E, Galinier A, Longin R, Deutscher J, Danchin A, Glaser P, Martin-Verstraete I (1999) The catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis. J Bacteriol 181:6889-6897. PubMed
  4. Shin BS, Choi SK, Park SH. 1999. Regulation of the Bacillus subtilis phosphotransacetylase gene. J. Biochem. 126:333-339. PubMed
  5. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed