YjbH

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  • Description: adaptor protein for ClpXP-catalyzed Spx degradation

Gene name yjbH
Synonyms
Essential
Product adaptor protein
Function adaptor protein for ClpX-ClpP-catalyzed Spx degradation
MW, pI 31 kDa, 5.206
Gene length, protein length 825 bp, 275 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
YjbH context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: adaptor protein for ClpXP-catalyzed Spx degradation PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
  • Effectors of protein activity: Zn atom is released upon treatment with strong oxidants PubMed
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Zuber, Oregon Health and Science, Univ., USA

Your additional remarks

References

  1. Garg et al. 2009. The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx. J. Bacteriol. 191: 1268-1277. PubMed
  2. Larsson, J. T., A. Rogstam, and C. von Wachenfeldt. 2007. YjbH is a novel negative effector of the disulphide stress regulator, Spx, in Bacillus subtilis. Mol. Microbiol. 66:669-684. PubMed