YvcJ

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  • Description: nucleotide-binding protein

Gene name yvcJ
Synonyms
Essential no
Product nucleotide-binding P-loop-containing protein
Function required for the expression of late competence genes
MW, pI 33 kDa, 6.702
Gene length, protein length 885 bp, 295 aa
Immediate neighbours yvcK, yvcI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvcJ context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU34770

Phenotypes of a mutant

reduced competence PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds and hydrolyzes nucleotides, required for the expression of late competence genes (comK, comS) PubMed
  • Protein family: UPF0042 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: very weak stimuation of expression by citrate and succinate PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector: pGP735 (N-terminal Strep-tag, purification from B. subtilis, for SPINE, in pGP380), available in Stülke lab
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Anne Galinier, University of Marseille, France

Your additional remarks

References