Difference between revisions of "Carbon core metabolism"

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{{CategoryTree
 
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* 2.2.2. [[Utilization of specific carbon sources]]
 
* 2.2.2. [[Utilization of specific carbon sources]]
 
|Related=
 
|Related=
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none
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* [[regulators of core metabolism]]
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* [[CcpA regulon]]
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* [[CcpC regulon]]
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* [[CggR regulon]]
 
|}}
 
|}}
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==Genes in this functional category==
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=== Glycolysis ===
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* ''[[cggR]]''
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* ''[[eno]]''
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* ''[[fbaA]]''
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* ''[[gapA]]''
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* ''[[glcT]]''
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* ''[[mgsA]]''
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* ''[[pfkA]]''
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* ''[[pgi]]''
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* ''[[pgk]]''
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* ''[[pgm]]''
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* ''[[ptsG]]''
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* ''[[pyk]]''
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* ''[[tpi]]''
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'''see the structures of glycolytic enzymes [http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html Glycolytic enzymes: molecules of the month]'''
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=== Gluconeogenesis ===
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* ''[[ccpN]]''
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* ''[[eno]]''
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* ''[[fbaA]]''
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* ''[[fbp]]''
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* ''[[gapB]]''
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* ''[[glpX]]''
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* ''[[pckA]]''
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* ''[[pgi]]''
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* ''[[pgk]]''
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* ''[[pgm]]''
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* ''[[tpi]]''
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* ''[[yqfL]]''
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* ''[[yvcK]]''
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=== Pentose phosphate pathway ===
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* ''[[gndA]]''
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* ''[[rpe]]''
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* ''[[tkt]]''
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* ''[[ykgB]]''
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* ''[[ywjH]]''
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* ''[[ywlF]]''
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* ''[[zwf]]''
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=== TCA cycle ===
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* ''[[ccpC]]''
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* ''[[citB]]''
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* ''[[citG]]''
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* ''[[citZ]]''
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* ''[[fsrA]]''
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* ''[[icd]]''
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* ''[[mdh]]''
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* ''[[odhA]]''
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* ''[[odhB]]''
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* ''[[pdhA]]''
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* ''[[pdhB]]''
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* ''[[pdhC]]''
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* ''[[pdhD]]''
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* ''[[pycA]]''
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* ''[[sdhA]]''
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* ''[[sdhB]]''
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* ''[[sdhC]]''
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*'' [[sucC]]''
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* ''[[sucD]]''
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=== Overflow metabolism ===
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* ''[[ackA]]''
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* ''[[alsD]]''
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* ''[[alsR]]''
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* ''[[alsS]]''
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* ''[[bdhA]]''
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* ''[[lctP]]''
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* ''[[ldh]]''
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* ''[[pta]]''
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* ''[[rex]]''
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== Carbon core metabolism in [http://subtiwiki.uni-goettingen.de/subtipathways.html ''Subti''Pathways]: [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central carbon metabolism]==
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==Important original publications==
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<pubmed>20933603 19193632 12850135 11489127 19917605 18586936 9131624 18302748 24727859 </pubmed>
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==Reviews==
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<pubmed> 11018147 19202299 17982469 16102602 22545791</pubmed>
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=Back to [[categories]]=

Latest revision as of 07:06, 15 April 2014

Parent categories
Neighbouring categories
Related categories

Genes in this functional category

Glycolysis

see the structures of glycolytic enzymes Glycolytic enzymes: molecules of the month

Gluconeogenesis

Pentose phosphate pathway

TCA cycle

Overflow metabolism

Carbon core metabolism in SubtiPathways: Central carbon metabolism

Important original publications

Hanna Meyer, Hendrikje Weidmann, Ulrike Mäder, Michael Hecker, Uwe Völker, Michael Lalk
A time resolved metabolomics study: the influence of different carbon sources during growth and starvation of Bacillus subtilis.
Mol Biosyst: 2014, 10(7);1812-23
[PubMed:24727859] [WorldCat.org] [DOI] (I p)

Frederik M Meyer, Jan Gerwig, Elke Hammer, Christina Herzberg, Fabian M Commichau, Uwe Völker, Jörg Stülke
Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon.
Metab Eng: 2011, 13(1);18-27
[PubMed:20933603] [WorldCat.org] [DOI] (I p)

Roelco J Kleijn, Joerg M Buescher, Ludovic Le Chat, Matthieu Jules, Stephane Aymerich, Uwe Sauer
Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis.
J Biol Chem: 2010, 285(3);1587-96
[PubMed:19917605] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632] [WorldCat.org] [DOI] (I p)

Simon Tännler, Eliane Fischer, Dominique Le Coq, Thierry Doan, Emmanuel Jamet, Uwe Sauer, Stéphane Aymerich
CcpN controls central carbon fluxes in Bacillus subtilis.
J Bacteriol: 2008, 190(18);6178-87
[PubMed:18586936] [WorldCat.org] [DOI] (I p)

Anne Goelzer, Fadia Bekkal Brikci, Isabelle Martin-Verstraete, Philippe Noirot, Philippe Bessières, Stéphane Aymerich, Vincent Fromion
Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis.
BMC Syst Biol: 2008, 2;20
[PubMed:18302748] [WorldCat.org] [DOI] (I e)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)

H Ludwig, G Homuth, M Schmalisch, F M Dyka, M Hecker, J Stülke
Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon.
Mol Microbiol: 2001, 41(2);409-22
[PubMed:11489127] [WorldCat.org] [DOI] (P p)

U Sauer, V Hatzimanikatis, J E Bailey, M Hochuli, T Szyperski, K Wüthrich
Metabolic fluxes in riboflavin-producing Bacillus subtilis.
Nat Biotechnol: 1997, 15(5);448-52
[PubMed:9131624] [WorldCat.org] [DOI] (P p)


Reviews

Maria Papagianni
Recent advances in engineering the central carbon metabolism of industrially important bacteria.
Microb Cell Fact: 2012, 11;50
[PubMed:22545791] [WorldCat.org] [DOI] (I e)

Yasutaro Fujita
Carbon catabolite control of the metabolic network in Bacillus subtilis.
Biosci Biotechnol Biochem: 2009, 73(2);245-59
[PubMed:19202299] [WorldCat.org] [DOI] (I p)

Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat Rev Microbiol: 2007, 5(12);917-27
[PubMed:17982469] [WorldCat.org] [DOI] (I p)

Uwe Sauer, Bernhard J Eikmanns
The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria.
FEMS Microbiol Rev: 2005, 29(4);765-94
[PubMed:16102602] [WorldCat.org] [DOI] (P p)

J Stülke, W Hillen
Regulation of carbon catabolism in Bacillus species.
Annu Rev Microbiol: 2000, 54;849-80
[PubMed:11018147] [WorldCat.org] [DOI] (P p)


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