Difference between revisions of "CotU"

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Revision as of 13:28, 16 May 2013

  • Description: spore coat protein

Gene name cotU
Synonyms ynzH
Essential no
Product spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotU
Interactions involving this protein in SubtInteract: CotU
MW, pI 11 kDa, 6.315
Gene length, protein length 258 bp, 86 aa
Immediate neighbours yncF, ynzJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YnzH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotU expression.png
























Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, GerR regulon

The gene

Basic information

  • Locus tag: BSU17670

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Giuseppina Cangiano, Antonio Mazzone, Loredana Baccigalupi, Rachele Isticato, Patrick Eichenberger, Maurilio De Felice, Ezio Ricca
Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis.
J Bacteriol: 2010, 192(13);3406-13
[PubMed:20435725] [WorldCat.org] [DOI] (I p)

Rachele Isticato, Assunta Pelosi, Maurilio De Felice, Ezio Ricca
CotE binds to CotC and CotU and mediates their interaction during spore coat formation in Bacillus subtilis.
J Bacteriol: 2010, 192(4);949-54
[PubMed:20023017] [WorldCat.org] [DOI] (I p)

Rachele Isticato, Assunta Pelosi, Rita Zilhão, Loredana Baccigalupi, Adriano O Henriques, Maurilio De Felice, Ezio Ricca
CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2008, 190(4);1267-75
[PubMed:18065538] [WorldCat.org] [DOI] (I p)

Erh-Min Lai, Nikhil D Phadke, Maureen T Kachman, Rebecca Giorno, Santiago Vazquez, Jenny A Vazquez, Janine R Maddock, Adam Driks
Proteomic analysis of the spore coats of Bacillus subtilis and Bacillus anthracis.
J Bacteriol: 2003, 185(4);1443-54
[PubMed:12562816] [WorldCat.org] [DOI] (P p)