DesR

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  • Description: two-component response regulator, regulation of cold shock expression of des

Gene name desR
Synonyms yocG
Essential no
Product two-component response regulator
Function regulation of cold shock expression of des
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 22 kDa, 4.885
Gene length, protein length 597 bp, 199 aa
Immediate neighbours desK, yocH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YocG context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU19200

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

lipid metabolism/ other, transcription factors and their control, cold stress proteins, membrane proteins, phosphoproteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription activation of the des operon when phosphorylated by DesK
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by DesK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced by cold shock (18-fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References