DhbE

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  • Description: 2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E) <br/><br/>
Gene name dhbE
Synonyms entE
Essential no
Product 2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E)
Function biosynthesis of the siderophore bacillibactin
MW, pI 59 kDa, 5.684
Gene length, protein length 1617 bp, 539 aa
Immediate neighbours dhbB, dhbC
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> DhbE context.gif
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/>

The gene

Basic information

  • Locus tag: BSU31980

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 1MDB (complex with DHB-adenylate), 1MDF
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks

References

<pubmed>12221282,11112781,,11790741,12354229, 8921902 8550523 20817675</pubmed>