Difference between revisions of "Fin"

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m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk)
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* '''Description:'''
 
** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/>
 
** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/>
 
** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/>
 
** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/>
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|style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination
 
|style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00540 fin]
 
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192   
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|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:fin_expression.png|500px]]
 
 
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|}
  
 
__TOC__
 
__TOC__
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* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 fin] {{PubMed|22383849}}
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* '''[[Sigma factor]]:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}}
 
 
* '''Sigma factor:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}}
 
  
 
* '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}}
 
* '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}}
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''
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* '''Additional information:'''  
  
 
=Biological materials =
 
=Biological materials =

Revision as of 10:14, 7 August 2012

  • Description:
    • suppressor of recU mutations, participates in the stabilization and or processing of holliday junction intermediates PubMed
    • alternative description: antagonist to SigF, required for the switch from SigF- to SigG-dependent gene expression in the forespore PubMed

Gene name subA
Synonyms yabK
Essential no
Product unknown
Function homologous recombination
MW, pI 8 kDa, 5.192
Gene length, protein length 228 bp, 76 aa
Immediate neighbours spoVC, mfd
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YabK context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

DNA repair/ recombination, sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00540

Phenotypes of a mutant

sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: expressed in two waves in the forespore (after two hours (SigF) and three hours (SigG) after the onset of sporulation) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Begoña Carrasco, M Castillo Cozar, Rudi Lurz, Juan C Alonso, Silvia Ayora
Genetic recombination in Bacillus subtilis 168: contribution of Holliday junction processing functions in chromosome segregation.
J Bacteriol: 2004, 186(17);5557-66
[PubMed:15317759] [WorldCat.org] [DOI] (P p)

B Carrasco, S Fernández, K Asai, N Ogasawara, J C Alonso
Effect of the recU suppressors sms and subA on DNA repair and homologous recombination in Bacillus subtilis.
Mol Genet Genomics: 2002, 266(5);899-906
[PubMed:11810266] [WorldCat.org] [DOI] (P p)

Additional publications: PubMed