Difference between revisions of "GerT"

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Revision as of 13:34, 16 May 2013

  • Description: spore coat protein, involved in germination

Gene name gerT
Synonyms yozR
Essential no
Product spore coat protein
Function germination
Gene expression levels in SubtiExpress: gerT
MW, pI 18 kDa, 6.342
Gene length, protein length 471 bp, 157 aa
Immediate neighbours yojE, yojB
Sequences Protein DNA DNA_with_flanks
Genetic context
YozR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GerT expression.png















Categories containing this gene/protein

sporulation proteins, germination, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU19490

Phenotypes of a mutant

  • mutants respond poorly to multiple germinants, impaired in early stage of germination PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: eamA transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot), first assembled in foci, then spread around the developing spore in a CotE-dependent manner PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: gerT (according to DBTBS)
  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Caitlin C Ferguson, Amy H Camp, Richard Losick
gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(21);7681-9
[PubMed:17720779] [WorldCat.org] [DOI] (P p)