GlnL

• Description: two-component response regulator, regulation of the glsA-glnT operon
  
  

Gene name	glnL
Synonyms	ycbB, yzgB
Essential	no
Product	two-component response regulator
Function	regulation of the glsA-glnT operon
Gene expression levels in SubtiExpress: glnL
Interactions involving this protein in SubtInteract: GlnL
MW, pI	35 kDa, 7.02
Gene length, protein length	942 bp, 314 aa
Immediate neighbours	glnK, ycbC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, utilization of amino acids, transcription factors and their control, phosphoproteins

The GlnL regulon:

• glsA-glnT

The gene

Basic information

• Locus tag: BSU02450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by GlnK on an Asp residue

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions: GlnK-GlnL

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P40759

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: glnL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Takenori Satomura, Daisuke Shimura, Kei Asai, Yoshito Sadaie, Kazutake Hirooka, Yasutaro Fujita
Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.
J Bacteriol: 2005, 187(14);4813-21
[PubMed:15995196] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)